LYMPHATIC LEUKEMIA

Metastatic acropachy in lymphatic leukemia.

By ROWLAND J. CALVERT AND ERIC SMITH P ERIPHERAL MANIFESTATIONS in lymphatic leukemia are well recognized. They may domimiat.e the climiical picture amid closely simulate other diseases. The unique amid confusimmg acral sighs imi this illustrative case merit detailed description. The only similar case recorded is that of Schit.tenhelm.’ Rhinophyma ‘as, how-ever, an additional feature in our pat...

L2C Guinea pig lymphatic leukemia: a "B" cell leukemia.

Chromosomes in lymphatic leukemia of C58 mice.

A larger size of chromosomes in neoplastic cells than in cells of the corresponding normal tissues has been observed in a number of instances (2, 4, 6, 8, 9, 11, 13). Among the several proposed explanations, that of Biesele, Poyner, and Painter (9) suggested that the chromosomes of malignant cells contained muhiples of the number of chromosome strands present in those of normal cells. In order ...

Tailoring of chronic lymphatic leukemia therapy.

Chronic lymphocytic leukemia (CLL) remains an incurable disease, with all patients who require therapy destined to relapse and understanding of the pathophysiology of chronic lymphocytic leukemia has advanced significantly. It is now clear that chronic lymphocytic leukemia is a relatively proliferative disorder that requires the help of its microenvironment to be maintained and to progress. The...

Expectancy for Life in Chronic Lymphatic Leukemia.

By ROBERT A. GREEN AND HUBERT DIXON T HERE ARE WIDE discrepancies in published data on survival in chronic leukemia, and it is not clear what the real prospects for survival are in this group of diseases. We have impressions of a variable chronicity, but there is need for standards if the results of new methods of treatment are to be meaningful, and it is important to know how valid the standar...